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Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
BACKGROUND: Pancreatic progenitors (PPs) co-expressing the two transcription factors (TFs) PDX1 and NKX6.1 are recognized as the indispensable precursors of functional pancreatic β cells. Here, we aimed to establish an efficient protocol for maximizing generation of PDX1(+)/NKX6.1(+) PPs from human...
Enregistré dans:
| Publié dans: | Stem Cell Res Ther |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5781269/ https://ncbi.nlm.nih.gov/pubmed/29361979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0759-z |
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