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Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major

The absence of tumor necrosis factor (TNF) causes lethal infection by Leishmania major in normally resistant C57BL/6J (B6.WT) mice. The underlying pathogenic mechanism of this fatal disease has so far remained elusive. We found that B6.WT mice deficient for the tnf gene (B6.TNF(−/−)) displayed not o...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Hu, Shanshan, Marshall, Cameron, Darby, Jocelyn, Wei, Wei, Lyons, Alan Bruce, Körner, Heinrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780437/
https://ncbi.nlm.nih.gov/pubmed/29403488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00001
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