Efficient immunity against Leishmania major in the absence of interleukin-6.

Mice genetically deficient in the pleiotropic cytokine interleukin-6 (IL-6) exhibit immunodeficiency against viral, bacterial, and fungal pathogens. When challenged with the protozoan parasite Leishmania major, IL-6-deficient mice controlled infection and mounted strong Th1 responses as efficiently...

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Detalles Bibliográficos
Main Authors: Moskowitz, N H, Brown, D R, Reiner, S L
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC175340/
https://ncbi.nlm.nih.gov/pubmed/9169788
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