Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms

Characterizing the contractile function of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) is key for advancing their utility for cellular disease models, promoting cell based heart repair, or developing novel pharmacological interventions targeting cardiac diseases. The aim of the pre...

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Publicat a:Front Physiol
Autors principals: Iorga, Bogdan, Schwanke, Kristin, Weber, Natalie, Wendland, Meike, Greten, Stephan, Piep, Birgit, dos Remedios, Cristobal G., Martin, Ulrich, Zweigerdt, Robert, Kraft, Theresia, Brenner, Bernhard
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780405/
https://ncbi.nlm.nih.gov/pubmed/29403388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01111
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