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EZH2 represses the B cell transcriptional program and regulates antibody secreting cell metabolism and antibody production()

Epigenetic remodeling is required during B cell differentiation. However, little is known about direct functions of epigenetic enzymes in antibody secreting cells (ASC) in vivo. Here, we examined ASC differentiation independent of T cell help and germinal center reactions using mice with inducible o...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Guo, Muyao, Price, Madeline J., Patterson, Dillon G., Barwick, Benjamin G., Haines, Robert R., Kania, Anna K., Bradley, John E., Randall, Troy D., Boss, Jeremy M., Scharer, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780247/
https://ncbi.nlm.nih.gov/pubmed/29288200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701470
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