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Cytochrome P450 1A1 and 1B1 promoter CpG island methylation regulates rat liver injury induced by isoniazid

DNA methylation is an important component of epigenetics that is involved in the occurrence and development of a variety of diseases. The present study aimed to clarify the relationship between cytochrome P450 (CYP)1A1 and CYP1B1 promoter CpG island methylation and isoniazid-induced liver injury in...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Li, Yanhui, Li, Yuhong, Zheng, Guoying, Zhu, Lingyan, Wang, Jishun, Mu, Shasha, Ren, Qi, Feng, Fumin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780152/
https://ncbi.nlm.nih.gov/pubmed/29115507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7929
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