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Wnt/β-catenin pathway activation and silencing of the APC gene in HPV-positive human cervical cancer-derived cells

Although persistent infections with high-risk human papilloma virus (HPV) constitute the most significant cofactor for the development of cervical cancer, they are insufficient on their own. Mutations or epigenetic inactivation of the tumor suppressor adenomatous polyposis coli (APC), the two acting...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Ayala-Calvillo, Erick, Mojica-Vázquez, Luis Humberto, García-Carrancá, Alejandro, González-Maya, Leticia
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780127/
https://ncbi.nlm.nih.gov/pubmed/29115417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7853
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