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Effect of prehypertensive losartan therapy on AT1R and ATRAP methylation of adipose tissue in the later life of high-fat-fed spontaneously hypertensive rats

Hypertension is frequently associated with metabolic disorders. The present study was designed to investigate the long-term effect of prehypertensive losartan therapy on metabolic disorders in high-fat-fed spontaneously hypertensive rats (SHRs), and to examine the role of epigenetic regulation of an...

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Detalles Bibliográficos
Publicado en:Mol Med Rep
Main Authors: Wang, Tingjun, Lian, Guili, Cai, Xiaoqi, Lin, Zhihong, Xie, Liangdi
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780120/
https://ncbi.nlm.nih.gov/pubmed/29257219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.8081
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