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Bardoxolone Methyl Prevents Fat Deposition and Inflammation in Brown Adipose Tissue and Enhances Sympathetic Activity in Mice Fed a High-Fat Diet

Obesity results in changes in brown adipose tissue (BAT) morphology, leading to fat deposition, inflammation, and alterations in sympathetic nerve activity. Bardoxolone methyl (BARD) has been extensively studied for the treatment of chronic diseases. We present for the first time the effects of oral...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Dinh, Chi H. L., Szabo, Alexander, Yu, Yinghua, Camer, Danielle, Zhang, Qingsheng, Wang, Hongqin, Huang, Xu-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488809/
https://ncbi.nlm.nih.gov/pubmed/26066016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu7064705
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