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Bardoxolone Methyl Prevents Fat Deposition and Inflammation in Brown Adipose Tissue and Enhances Sympathetic Activity in Mice Fed a High-Fat Diet

Obesity results in changes in brown adipose tissue (BAT) morphology, leading to fat deposition, inflammation, and alterations in sympathetic nerve activity. Bardoxolone methyl (BARD) has been extensively studied for the treatment of chronic diseases. We present for the first time the effects of oral...

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Bibliografske podrobnosti
izdano v:Nutrients
Main Authors: Dinh, Chi H. L., Szabo, Alexander, Yu, Yinghua, Camer, Danielle, Zhang, Qingsheng, Wang, Hongqin, Huang, Xu-Feng
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488809/
https://ncbi.nlm.nih.gov/pubmed/26066016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu7064705
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