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Silencing of histone methyltransferase NSD3 reduces cell viability in osteosarcoma with induction of apoptosis

NSD3 is a histone lysine methyltransferase that methylates histone H3 at lysine 36. NSD3 is located at chromosome 8p11.23, the locus that exhibits strong cancer relevance. Thus, NSD3 is likely involved in multiple human cancers. Nevertheless, its roles in human carcinogenesis remain unknown. In the...

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Détails bibliographiques
Publié dans:Oncol Rep
Auteurs principaux: Liu, Zhiwei, Piao, Lianhua, Zhuang, Ming, Qiu, Xubin, Xu, Xiaoshuang, Zhang, Dawei, Liu, Mengmeng, Ren, Ding
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780032/
https://ncbi.nlm.nih.gov/pubmed/28901481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5936
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