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Silencing of histone methyltransferase NSD3 reduces cell viability in osteosarcoma with induction of apoptosis

NSD3 is a histone lysine methyltransferase that methylates histone H3 at lysine 36. NSD3 is located at chromosome 8p11.23, the locus that exhibits strong cancer relevance. Thus, NSD3 is likely involved in multiple human cancers. Nevertheless, its roles in human carcinogenesis remain unknown. In the...

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Podrobná bibliografie
Vydáno v:Oncol Rep
Hlavní autoři: Liu, Zhiwei, Piao, Lianhua, Zhuang, Ming, Qiu, Xubin, Xu, Xiaoshuang, Zhang, Dawei, Liu, Mengmeng, Ren, Ding
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780032/
https://ncbi.nlm.nih.gov/pubmed/28901481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5936
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