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Semi-random mutagenesis profile of BCR-ABL during imatinib resistance acquirement in K562 cells
Although imatinib is effective in chronic myeloid leukemia treatment, imatinib resistance due to the T315I mutation and/or other mutations is a challenge to be overcome. However, how DNA mutation occurs, particularly the T315I mutation, remains unclear. In the current study, the mutagenesis of BCR-A...
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| Publicado no: | Mol Med Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5779997/ https://ncbi.nlm.nih.gov/pubmed/29152650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7835 |
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