Neuroprotective effect of chondroitin sulfate on SH-SY5Y cells overexpressing wild-type or A53T mutant α-synuclein

Accumulation of α-synuclein (α-SYN) is a common pathology for Parkinson's disease (PD). There is abundant evidence that the toxic-gain-of-function of α-SYN's is associated with aggregation and consequent effects. To assess the potential of chondroitin sulfate (CS) in this regard, the prese...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Ju, Chuanxia, Gao, Jianjun, Hou, Lin, Wang, Lei, Zhang, Fang, Sun, Fusheng, Zhang, Tingting, Xu, Pingping, Shi, Zhenyan, Hu, Fang, Zhang, Congxiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779948/
https://ncbi.nlm.nih.gov/pubmed/28990084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7725
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