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Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome

It is established that the physiological effects of insulin are primarily mediated by the insulin signaling pathway. However, a defective insulin signaling is closely associated with the clinical manifestations of polycystic ovary syndrome (PCOS), which include excess androgen levels, insulin resist...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Wang, Fan, Wang, Shaobing, Zhang, Zhenghong, Lin, Qingqiang, Liu, Yiping, Xiao, Yijun, Xiao, Kaizhuan, Wang, Zhengchao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779901/
https://ncbi.nlm.nih.gov/pubmed/28990055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7678
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