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The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection

Trypanosoma cruzi, the etiological agent of Chagas disease, consumes glucose and amino acids depending on the environmental availability of each nutrient during its complex life cycle. For example, amino acids are the major energy and carbon sources in the intracellular stages of the T. cruzi parasi...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Crispim, Marcell, Damasceno, Flávia Silva, Hernández, Agustín, Barisón, María Julia, Pretto Sauter, Ismael, Souza Pavani, Raphael, Santos Moura, Alexandre, Pral, Elizabeth Mieko Furusho, Cortez, Mauro, Elias, Maria Carolina, Silber, Ariel Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779702/
https://ncbi.nlm.nih.gov/pubmed/29320490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006170
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