Memantine, an Antagonist of the NMDA Glutamate Receptor, Affects Cell Proliferation, Differentiation and the Intracellular Cycle and Induces Apoptosis in Trypanosoma cruzi

Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi and affects approximately 10 million people in endemic areas of Mexico and Central and South America. Currently available chemotherapies are limited to two compounds: Nifurtimox and Benznidazole. Both drugs reduce the symptom...

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Detalhes bibliográficos
Main Authors: Damasceno, Flávia Silva, Barisón, María Julia, Pral, Elisabeth Mieko Furusho, Paes, Lisvane Silva, Silber, Ariel Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937314/
https://ncbi.nlm.nih.gov/pubmed/24587468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002717
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