Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection

Burden of pneumonia caused by Streptococcus pneumoniae remains high despite the availability of conjugate vaccines. Mucosal immunization targeting the lungs is an attractive alternative for the induction of local immune responses to improve protection against pneumonia. Our group had previously desc...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Rodrigues, Tasson C., Oliveira, Maria Leonor S., Soares-Schanoski, Alessandra, Chavez-Rico, Stefanni L., Figueiredo, Douglas B., Gonçalves, Viviane M., Ferreira, Daniela M., Kunda, Nitesh K., Saleem, Imran Y., Miyaji, Eliane N.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779684/
https://ncbi.nlm.nih.gov/pubmed/29360883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191692
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