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Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E(−/−) Mice
OBJECTIVE—: The MC1-R (melanocortin 1 receptor) is expressed by monocytes and macrophages where it mediates anti-inflammatory actions. MC1-R also protects against macrophage foam cell formation primarily by promoting cholesterol efflux through the ABCA1 (ATP-binding cassette transporter subfamily A...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5779319/ https://ncbi.nlm.nih.gov/pubmed/29284608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310418 |
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