Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages

BACKGROUND: The melanocortin 1 receptor (MC1-R) is expressed by monocytes and macrophages, where it exerts anti-inflammatory actions upon stimulation with its natural ligand α-melanocyte-stimulating hormone (α-MSH). The present study was designed to investigate the specific role of MC1-R in the cont...

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Publicado no:Circulation
Principais autores: Rinne, Petteri, Rami, Martina, Nuutinen, Salla, Santovito, Donato, van der Vorst, Emiel P.C., Guillamat-Prats, Raquel, Lyytikäinen, Leo-Pekka, Raitoharju, Emma, Oksala, Niku, Ring, Larisa, Cai, Minying, Hruby, Victor J., Lehtimäki, Terho, Weber, Christian, Steffens, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518461/
https://ncbi.nlm.nih.gov/pubmed/28450348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.025889
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