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Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain

In the adult brain, both neurons and oligodendrocytes can be generated from neural stem cells located within the Sub-Ventricular Zone (SVZ). Physiological signals regulating neuronal versus glial fate are largely unknown. Here we report that a thyroid hormone (T(3))-free window, with or without a de...

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Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Remaud, Sylvie, Ortiz, Fernando C, Perret-Jeanneret, Marine, Aigrot, Marie-Stéphane, Gothié, Jean-David, Fekete, Csaba, Kvárta-Papp, Zsuzsanna, Gereben, Balázs, Langui, Dominique, Lubetzki, Catherine, Angulo, Maria Cecilia, Zalc, Bernard, Demeneix, Barbara
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779229/
https://ncbi.nlm.nih.gov/pubmed/28875931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29996
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