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Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain

In the adult brain, both neurons and oligodendrocytes can be generated from neural stem cells located within the Sub-Ventricular Zone (SVZ). Physiological signals regulating neuronal versus glial fate are largely unknown. Here we report that a thyroid hormone (T(3))-free window, with or without a de...

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Publicat a:eLife
Autors principals: Remaud, Sylvie, Ortiz, Fernando C, Perret-Jeanneret, Marine, Aigrot, Marie-Stéphane, Gothié, Jean-David, Fekete, Csaba, Kvárta-Papp, Zsuzsanna, Gereben, Balázs, Langui, Dominique, Lubetzki, Catherine, Angulo, Maria Cecilia, Zalc, Bernard, Demeneix, Barbara
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779229/
https://ncbi.nlm.nih.gov/pubmed/28875931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29996
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