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A Reductionist Metastasis-on-a-Chip Platform for In Vitro Tumor Progression Modeling and Drug Screening

Current animal and 2-D cell culture models employed in metastasis research and drug discovery remain poor mimics of human cancer physiology. Here we describe a “metastasis-on-a-chip” system allowing real time tracking of fluorescent colon cancer cells migrating from hydrogel-fabricated gut construct...

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發表在:Biotechnol Bioeng
Main Authors: Skardal, Aleksander, Devarasetty, Mahesh, Forsythe, Steven, Atala, Anthony, Soker, Shay
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778914/
https://ncbi.nlm.nih.gov/pubmed/26888480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25950
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