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Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway

Previous studies have suggested that metformin, a biguanide family member widely used as an oral antidiabetic drug, may inhibit proliferation and induce apoptosis in certain types of cancer cell. However, the molecular mechanisms underlying metformin-associated anticancer effects, and in particular...

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Bibliografische gegevens
Gepubliceerd in:Oncol Lett
Hoofdauteurs: He, Yindi, Tan, Xiaojun, Hu, Hui, Wang, Qinjia, Hu, Xi, Cai, Xianbin, Guan, Yinghong, Chen, Binming, Jing, Xubin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778829/
https://ncbi.nlm.nih.gov/pubmed/29435022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7699
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