Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In Vivo

Esophageal squamous cell carcinomas (ESCC) have become a severe threat to health and the current treatments for ESCC are frequently not effective. Recent epidemiological studies suggest that the anti-hyperglycemic agent metformin may reduce the risk of developing cancer, including ESCC, among diabet...

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Foilsithe in:PLoS One
Main Authors: Cai, Xianbin, Hu, Xi, Tan, Xiaojun, Cheng, Weijie, Wang, Qinjia, Chen, Xiaofeng, Guan, Yinghong, Chen, Chong, Jing, Xubin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510392/
https://ncbi.nlm.nih.gov/pubmed/26196392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133349
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