FAM3B/PANDER inhibits cell death and increases prostate tumor growth by modulating the expression of Bcl-2 and Bcl-X(L) cell survival genes

BACKGROUND: FAM3B/PANDER is a novel cytokine-like protein that induces apoptosis in insulin-secreting beta-cells. Since in silico data revealed that FAM3B can be expressed in prostate tumors, we evaluated the putative role of this cytokine in prostate tumor progression. METHODS: FAM3B expression was...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Maciel-Silva, Paula, Caldeira, Izabela, de Assis Santos, Icaro, Carreira, Ana Claudia Oliveira, Siqueira, Flavia Ramos, Antonioli, Eliane, Goldberg, Anna Carla, Belizário, José Ernesto, Garay-Malpartida, Humberto Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778767/
https://ncbi.nlm.nih.gov/pubmed/29357840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3950-9
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