Targeted Disruption of Pancreatic-Derived Factor (PANDER, FAM3B) Impairs Pancreatic β-Cell Function

OBJECTIVE: Pancreatic-derived factor (PANDER, FAM3B) is a pancreatic islet-specific cytokine-like protein that is secreted from β-cells upon glucose stimulation. The biological function of PANDER is unknown, and to address this we generated and characterized a PANDER knockout mouse. RESEARCH DESIGN...

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Detalhes bibliográficos
Main Authors: Robert-Cooperman, Claudia E., Carnegie, Jason R., Wilson, Camella G., Yang, Jichun, Cook, Joshua R., Wu, Jianmei, Young, Robert A., Wolf, Bryan A., Burkhardt, Brant R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927943/
https://ncbi.nlm.nih.gov/pubmed/20566664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1552
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