Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells

BACKGROUND: Despite the high cure rate of T cell acute lymphoblastic leukemia (T-ALL), drug resistance to chemotherapy remains a significant clinical problem. Bone marrow mesenchymal stem cells (MSCs) protect leukemic cells from chemotherapy, but the underlying mechanisms are poorly understood. In t...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Hematol Oncol
Auteurs principaux: Wang, Jiancheng, Liu, Xin, Qiu, Yuan, Shi, Yue, Cai, Jianye, Wang, Boyan, Wei, Xiaoyue, Ke, Qiong, Sui, Xin, Wang, Yi, Huang, Yinong, Li, Hongyu, Wang, Tao, Lin, Ren, Liu, Qifa, Xiang, Andy Peng
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778754/
https://ncbi.nlm.nih.gov/pubmed/29357914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0554-z
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