ERK/Drp1-dependent mitochondrial fission is involved in the MSC-induced drug resistance of T-cell acute lymphoblastic leukemia cells

The bone marrow microenvironment facilitates the proliferation and survival of leukemia cells, contributing to disease relapse. Bone marrow-derived mesenchymal stem cells (MSCs) are well known to promote cancer chemoresistance via soluble factors and cell adhesion. However, little is known about the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Cai, Jianye, Wang, Jiancheng, Huang, Yinong, Wu, Haoxiang, Xia, Ting, Xiao, Jiaqi, Chen, Xiaoyong, Li, Hongyu, Qiu, Yuan, Wang, Yingnan, Wang, Tao, Xia, Huimin, Zhang, Qi, Xiang, Andy Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260898/
https://ncbi.nlm.nih.gov/pubmed/27831567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.370
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