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Alternative start and termination sites of transcription drive most transcript isoform differences across human tissues

Most human genes generate multiple transcript isoforms. The differential expression of these isoforms can help specify cell types. Diverse transcript isoforms arise from the use of alternative transcription start sites, polyadenylation sites and splice sites; however, the relative contribution of th...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Reyes, Alejandro, Huber, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778607/
https://ncbi.nlm.nih.gov/pubmed/29202200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1165
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