Llwytho...

Alternative start sites downstream of nonsense mutations drive antigen presentation and tolerance induction to C-terminal epitopes

Cytotoxic T-cell (CTL) responses to the transgene product remain an active area of concern for the gene therapy field. A patient’s underlying genetic mutation may influence the qualitative nature of these potentially destructive T-cell responses. Individuals with a mutation that introduces a prematu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Ashley, Scott N., Somanathan, Suryanarayan, Hinderer, Christian, Arias, Maxwell, McMenamin, Deirdre, Draper, Christine, Wilson, James M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508590/
https://ncbi.nlm.nih.gov/pubmed/28500077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601131
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