Načítá se...

Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes

The human CST (Ctc1, Stn1 and Ten1) complex binds the telomeric overhang and regulates telomere length by promoting C-strand replication and inhibiting telomerase-dependent G-strand synthesis. Structural and biochemical studies on the human Stn1 and Ten1 complex revealed its mechanism of assembly an...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Shastrula, Prashanth K, Rice, Cory T, Wang, Zhuo, Lieberman, Paul M, Skordalakes, Emmanuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778599/
https://ncbi.nlm.nih.gov/pubmed/29228254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1213
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!