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Cdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere Maintenance

Cdc13 is an essential yeast protein required for telomere length regulation and genome stability. It does so via its telomere capping properties and by regulating telomerase access to the telomeres. The crystal structure of the S. cerevisiae Cdc13 domain located between the recruitment and DNA bindi...

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Main Authors: Mason, Mark, Wanat, Jennifer J., Harper, Sandy, Schultz, David C., Speicher, David W., Johnson, F. Brad, Skordalakes, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545062/
https://ncbi.nlm.nih.gov/pubmed/23177925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.10.012
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