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Development of matrix metalloproteinase-targeted probes for lung inflammation detection with positron emission tomography

As matrix metalloproteinases (MMPs), especially MMP-9 and MMP-12 are involved in the pathological processes associated with chronic obstructive pulmonary disease (COPD), we developed a novel radiofluorinated probe, (18)F-IPFP, for MMPs-targeted positron emission tomography (PET). (18)F-IPFP was desi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kondo, Naoya, Temma, Takashi, Aita, Kazuki, Shimochi, Saeka, Koshino, Kazuhiro, Senda, Michio, Iida, Hidehiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778071/
https://ncbi.nlm.nih.gov/pubmed/29358724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19890-1
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