Decoding the centromeric nucleosome through CENP-N

Centromere protein (CENP) A, a histone H3 variant, is a key epigenetic determinant of chromosome domains known as centromeres. Centromeres nucleate kinetochores, multi-subunit complexes that capture spindle microtubules to promote chromosome segregation during mitosis. Two kinetochore proteins, CENP...

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Udgivet i:eLife
Main Authors: Pentakota, Satyakrishna, Zhou, Keda, Smith, Charlotte, Maffini, Stefano, Petrovic, Arsen, Morgan, Garry P, Weir, John R, Vetter, Ingrid R, Musacchio, Andrea, Luger, Karolin
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Structural Biology and Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777823/
https://ncbi.nlm.nih.gov/pubmed/29280735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33442
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