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Regular physical activity prevents development of chronic muscle pain through modulation of supraspinal opioid and serotonergic mechanisms

INTRODUCTION: It is generally believed that exercise produces its effects by activating central opioid receptors; there are little data that support this claim. The periaqueductal gray (PAG) and rostral ventromedial medulla (RVM) are key nuclei in opioid-induced analgesia, and opioids interact with...

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Bibliografiske detaljer
Udgivet i:Pain Rep
Main Authors: Brito, Renan G., Rasmussen, Lynn A., Sluka, Kathleen A.
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777681/
https://ncbi.nlm.nih.gov/pubmed/29392233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PR9.0000000000000618
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