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Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission

Unlike in most pathogens, multiple-strain (polygenomic) infections of P. falciparum are frequently composed of genetic siblings. These genetic siblings are the result of sexual reproduction and can coinfect the same host when cotransmitted by the same mosquito. The degree with which coinfecting stra...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Wong, Wesley, Wenger, Edward A., Hartl, Daniel L., Wirth, Dyann F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777656/
https://ncbi.nlm.nih.gov/pubmed/29315306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005923
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