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Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission

Unlike in most pathogens, multiple-strain (polygenomic) infections of P. falciparum are frequently composed of genetic siblings. These genetic siblings are the result of sexual reproduction and can coinfect the same host when cotransmitted by the same mosquito. The degree with which coinfecting stra...

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Pubblicato in:PLoS Comput Biol
Autori principali: Wong, Wesley, Wenger, Edward A., Hartl, Daniel L., Wirth, Dyann F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777656/
https://ncbi.nlm.nih.gov/pubmed/29315306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005923
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