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KRAS Cold Turkey: Using microRNAs to target KRAS-addicted cancer

Human cancers are driven by genetic mutations which cause aberrant activation of pro-growth pathways. Although cancers are uniquely dependent on the pro-growth signaling from oncogenic pathways, efforts to directly target these have been largely unsuccessful. One of the most common and drug resistan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA Dis
Hauptverfasser: Jones, Matthew F., Hara, Toshifumi, Lal, Ashish
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777587/
https://ncbi.nlm.nih.gov/pubmed/29367950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/rd.539
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