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Metabolic Barriers to T Cell Function in Tumors

The metabolic programs that drive T cell functions are exquisitely sensitive to cell intrinsic and extrinsic factors, allowing T cells to respond in a fine-tuned manner to a variety of immune challenges and conditions. However, many of the factors essential for effector T cell function are perturbed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Sugiura, Ayaka, Rathmell, Jeffrey C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777533/
https://ncbi.nlm.nih.gov/pubmed/29311381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701041
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