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The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy
Breakthroughs in anti-tumor immunity have led to unprecedented advances in immunotherapy, yet it is now clear that the tumor microenvironment (TME) restrains immunity. T cells must substantially increase nutrient uptake to mount a proper immune response and failure to obtain sufficient nutrients or...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7200151/ https://ncbi.nlm.nih.gov/pubmed/32367803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55185 |
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