Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy

BACKGROUND: Cabozantinib is a potent, multitarget inhibitor of MET and vascular endothelial growth factor receptor 2 (VEGFR2). This open-label, phase II trial evaluated cabozantinib in patients with recurrent or progressive glioblastoma (GBM). METHODS: Patients were initially enrolled to a starting...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Cloughesy, Timothy F, Drappatz, Jan, de Groot, John, Prados, Michael D, Reardon, David A, Schiff, David, Chamberlain, Marc, Mikkelsen, Tom, Desjardins, Annick, Ping, Jerry, Holland, Jaymes, Weitzman, Ron, Wen, Patrick Y
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777491/
https://ncbi.nlm.nih.gov/pubmed/29036345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox151
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