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Carnosic acid, an inducer of NAD(P)H quinone oxidoreductase 1, enhances the cytotoxicity of β-lapachone in melanoma cell lines

NAD(P)H quinone oxidoreductase 1 (NQO1)-dependent antitumor drugs such as β-lapachone (β-lap) are attractive candidates for cancer chemotherapy because several tumors exhibit higher expression of NQO1 than adjacent tissues. Although the association between NQO1 and β-lap has been elucidated, the eff...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Arakawa, Nobuyuki, Okubo, Ayaka, Yasuhira, Shinji, Takahashi, Kazuhiro, Amano, Hiroo, Akasaka, Toshihide, Masuda, Tomoyuki, Shibazaki, Masahiko, Maesawa, Chihaya
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777343/
https://ncbi.nlm.nih.gov/pubmed/29434949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7618
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