Augmentation of antibody-dependent cellular cytotoxicity with defucosylated monoclonal antibodies in patients with GI-tract cancer

Enhancement of antibody-dependent cellular cytotoxicity (ADCC) with some modalities may be a promising approach to enhance the efficacy of therapeutic monoclonal antibodies (mAbs). It has previously been demonstrated that the removal of fucose from antibody oligosaccharides (defucosylation) leads to...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Oncol Lett
Main Authors: Nakajima, Takahiro, Okayama, Hirokazu, Ashizawa, Mai, Noda, Masaru, Aoto, Keita, Saito, Motonobu, Monma, Tomoyuki, Ohki, Shinji, Shibata, Masahiko, Takenoshita, Seiichi, Kono, Koji
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2018
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777280/
https://ncbi.nlm.nih.gov/pubmed/29434980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7556
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla