Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions

Elevated expression of human enhancer filamentation 1 (HEF1; also known as NEDD9 or Cas-L) is an essential stimulus for the metastatic process of various solid tumors. This process requires HEF1 localization to focal adhesions (FAs). Although the association of HEF1 with FAs is considered to play a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lee, Kyung Ho, Hwang, Jeong-Ah, Kim, Sun-Ok, Kim, Jung Hee, Shin, Sang Chul, Kim, Eunice EunKyeong, Lee, Kyung S., Rhee, Kunsoo, Jeon, Byeong Hwa, Bang, Jeong Kyu, Cha-Molstad, Hyunjoo, Soung, Nak-Kyun, Jang, Jae-Hyuk, Ko, Sung-Kyun, Lee, Hee Gu, Ahn, Jong Seog, Kwon, Yong Tae, Kim, Bo Yeon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777258/
https://ncbi.nlm.nih.gov/pubmed/29191835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802587
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