Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates

Proper chromosome alignment and segregation during mitosis depend on cohesion between sister chromatids, mediated by the cohesin protein complex, which also plays crucial roles in diverse genome maintenance pathways. Current models attribute DNA binding by cohesin to entrapment of dsDNA by the cohes...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Countryman, Preston, Fan, Yanlin, Gorthi, Aparna, Pan, Hai, Strickland, Evelyn, Kaur, Parminder, Wang, Xuechun, Lin, Jiangguo, Lei, Xiaoying, White, Christian, You, Changjiang, Wirth, Nicolas, Tessmer, Ingrid, Piehler, Jacob, Riehn, Robert, Bishop, Alexander J.R., Tao, Yizhi Jane, Wang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777247/
https://ncbi.nlm.nih.gov/pubmed/29175904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806406
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