Analyses of the FranceCoag cohort support differences in immunogenicity among one plasma-derived and two recombinant factor VIII brands in boys with severe hemophilia A

Around one third of boys with severe hemophilia A develop inhibitors (neutralizing antibodies) against their therapeutic factor VIII product. This adverse effect may result in more life-threatening bleeding, disability, impaired quality of life, and costly care. We compared the incidence of inhibito...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Calvez, Thierry, Chambost, Hervé, d’Oiron, Roseline, Dalibard, Vincent, Demiguel, Virginie, Doncarli, Alexandra, Gruel, Yves, Huguenin, Yoann, Lutz, Patrice, Rothschild, Chantal, Vinciguerra, Christine, Goudemand, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777205/
https://ncbi.nlm.nih.gov/pubmed/29025913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.174706
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