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Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration

How organs maintain and restore functional integrity during ordinary tissue turnover or following injury represents a central biological problem. The maintenance of taste sensory organs in the tongue was shown 140 years ago to depend on innervation from distant ganglion neurons, but the underlying m...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lu, Wan-Jin, Mann, Randall K., Nguyen, Allison, Bi, Tingting, Silverstein, Max, Tang, Jean Y., Chen, Xiaoke, Beachy, Philip A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777079/
https://ncbi.nlm.nih.gov/pubmed/29279401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719109115
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