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Single-molecule FRET studies on the cotranscriptional folding of a thiamine pyrophosphate riboswitch

Because RNAs fold as they are being synthesized, their transcription rate can affect their folding. Here, we report the results of single-molecule fluorescence studies that characterize the ligand-dependent cotranscriptional folding of the Escherichia coli thiM riboswitch that regulates translation....

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Uhm, Heesoo, Kang, Wooyoung, Ha, Kook Sun, Kang, Changwon, Hohng, Sungchul
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777041/
https://ncbi.nlm.nih.gov/pubmed/29279370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712983115
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