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Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration

Filopodia have a key role in sensing both chemical and mechanical cues in surrounding extracellular matrix (ECM). However, quantitative understanding is still missing in the filopodial mechanosensing of local ECM stiffness, resulting from dynamic interactions between filopodia and the surrounding 3D...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kim, Min-Cheol, Silberberg, Yaron R., Abeyaratne, Rohan, Kamm, Roger D., Asada, H. Harry
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776995/
https://ncbi.nlm.nih.gov/pubmed/29295934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717230115
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