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Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration
Filopodia have a key role in sensing both chemical and mechanical cues in surrounding extracellular matrix (ECM). However, quantitative understanding is still missing in the filopodial mechanosensing of local ECM stiffness, resulting from dynamic interactions between filopodia and the surrounding 3D...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776995/ https://ncbi.nlm.nih.gov/pubmed/29295934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717230115 |
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